Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50001194
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271690(CHEMBL222649)
Affinity DataIC50: 2nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271690(CHEMBL222649)
Affinity DataIC50: 3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271681(CHEMBL4129611)
Affinity DataIC50: 15nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271692(CHEMBL4126611)
Affinity DataIC50: 42nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50: 44nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271697(CHEMBL4128244)
Affinity DataIC50: 48nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271696(CHEMBL4125776)
Affinity DataIC50: 77nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271685(CHEMBL4128887)
Affinity DataIC50: 84nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271694(CHEMBL4127007)
Affinity DataIC50: 86nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271693(CHEMBL4126455)
Affinity DataIC50: 92nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271714(CHEMBL4126546)
Affinity DataIC50: 93nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271714(CHEMBL4126546)
Affinity DataIC50: 110nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271689(CHEMBL4130028)
Affinity DataIC50: 110nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19861((2S)-N-(cyanomethyl)-4-methyl-2-(phenylformamido)p...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271696(CHEMBL4125776)
Affinity DataIC50: 120nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM232239(N-3-trifluoromethylbenzoyl-L-leucine-glycine nitri...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271691(CHEMBL4129884)
Affinity DataIC50: 130nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271686(CHEMBL4126741)
Affinity DataIC50: 140nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271688(CHEMBL4130249)
Affinity DataIC50: 140nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271685(CHEMBL4128887)
Affinity DataIC50: 160nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271681(CHEMBL4129611)
Affinity DataIC50: 180nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271709(CHEMBL4126824)
Affinity DataIC50: 190nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271695(CHEMBL4127142)
Affinity DataIC50: 240nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271682(CHEMBL4130087)
Affinity DataIC50: 250nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271698(CHEMBL4128116)
Affinity DataIC50: 280nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271682(CHEMBL4130087)
Affinity DataIC50: 280nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM232239(N-3-trifluoromethylbenzoyl-L-leucine-glycine nitri...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19861((2S)-N-(cyanomethyl)-4-methyl-2-(phenylformamido)p...)
Affinity DataIC50: 350nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271697(CHEMBL4128244)
Affinity DataIC50: 360nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271688(CHEMBL4130249)
Affinity DataIC50: 400nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271709(CHEMBL4126824)
Affinity DataIC50: 420nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271686(CHEMBL4126741)
Affinity DataIC50: 530nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271698(CHEMBL4128116)
Affinity DataIC50: 540nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271713(CHEMBL4129822)
Affinity DataIC50: 590nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271713(CHEMBL4129822)
Affinity DataIC50: 660nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271711(CHEMBL4129022)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271710(CHEMBL4126675)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271693(CHEMBL4126455)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271712(CHEMBL4128869)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271692(CHEMBL4126611)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271691(CHEMBL4129884)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271711(CHEMBL4129022)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271689(CHEMBL4130028)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271683(CHEMBL4127618)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271712(CHEMBL4128869)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271683(CHEMBL4127618)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271684(CHEMBL4130234)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271695(CHEMBL4127142)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271694(CHEMBL4127007)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
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