Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50001195
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271717(CHEMBL4127840)
Affinity DataIC50: 360nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271715(CHEMBL4125701)
Affinity DataKi:  3.57E+3nMAssay Description:Irreversible inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate incubated for 5 to 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271717(CHEMBL4127840)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant assessed as decrease in transpeptidation of IsdA (64 to 323 residues) incubated for 1.25 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant assessed as decrease in transpeptidation of IsdA (64 to 323 residues) incubated for 1.25 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271715(CHEMBL4125701)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271715(CHEMBL4125701)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant assessed as decrease in transpeptidation of IsdA (64 to 323 residues) incubated for 1.25 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271716(CHEMBL4129079)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271716(CHEMBL4129079)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant assessed as decrease in transpeptidation of IsdA (64 to 323 residues) incubated for 1.25 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50271725(CHEMBL4127684)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed