Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50002978
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465354(CHEMBL4293045 | US10669276, Example 4)
Affinity DataEC50:  7nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465355(CHEMBL4285214 | US10669276, Example 1)
Affinity DataEC50:  5nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465356(CHEMBL4289270 | US10669276, Example 16)
Affinity DataEC50:  30nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465357(CHEMBL4283902 | US10669276, Example 25)
Affinity DataEC50:  8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465358(CHEMBL4284649 | US10669276, Example 31)
Affinity DataEC50:  15nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465359(CHEMBL4279052 | US10669276, Example 11)
Affinity DataEC50:  33nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465360(CHEMBL4294948 | US10669276, Example 28)
Affinity DataEC50:  8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465361(CHEMBL4293005)
Affinity DataEC50:  14nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465362(CHEMBL4286544)
Affinity DataEC50:  8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465363(CHEMBL4278310 | US10669276, Example 35)
Affinity DataEC50:  13nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed