Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50002984
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataEC50:  410nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465408(CHEMBL4288076)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465404(CHEMBL4279657)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465406(CHEMBL4281734)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC3 (unknown origin) using substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465400(CHEMBL4289614)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465402(CHEMBL4283574)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465405(CHEMBL4287028)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC6 (unknown origin) using substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465406(CHEMBL4281734)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465408(CHEMBL4288076)
Affinity DataIC50: 113nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465401(CHEMBL4290006)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465403(CHEMBL4277764)
Affinity DataIC50: 123nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465401(CHEMBL4290006)
Affinity DataIC50: 133nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465402(CHEMBL4283574)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465400(CHEMBL4289614)
Affinity DataIC50: 168nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 179nMAssay Description:Inhibition of HDAC2 (unknown origin) using substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465404(CHEMBL4279657)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465398(CHEMBL4277863)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465410(CHEMBL4285161)
Affinity DataIC50: 262nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465403(CHEMBL4277764)
Affinity DataIC50: 308nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465398(CHEMBL4277863)
Affinity DataIC50: 604nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465409(CHEMBL4292998)
Affinity DataIC50: 633nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465411(CHEMBL4294936)
Affinity DataIC50: 895nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465407(CHEMBL4288519)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed