Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50002755
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 180nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462559(CHEMBL4238968)
Affinity DataIC50: 200nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 350nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462559(CHEMBL4238968)
Affinity DataIC50: 410nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462561(CHEMBL4240644)
Affinity DataIC50: 869nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462562(CHEMBL4246425)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462558(CHEMBL4244469)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462564(CHEMBL4243545)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462556(CHEMBL4250689)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462563(CHEMBL4240740)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462566(CHEMBL4239322)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462557(CHEMBL4248337)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 10 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 20 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462565(CHEMBL4240164)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SAH probe binding to NNMT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 40 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462560(CHEMBL4238535)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462560(CHEMBL4238535)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 80 uM SAM addition followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50462555(CHEMBL4240266)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate pretreated for 1 hr at 3 mins post 160 uM SAM addition followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed