Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50002243
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455853(CHEMBL4202828)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455854(CHEMBL4203464)
Affinity DataEC50:  9nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455852(CHEMBL4209452)
Affinity DataEC50:  29nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455851(CHEMBL4203540)
Affinity DataEC50:  10nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455855(CHEMBL4202601)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at VDR in human MCF7 cells assessed as increase in transcription of CYP24A1 gene after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455852(CHEMBL4209452)
Affinity DataIC50: 3.5nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455853(CHEMBL4202828)
Affinity DataIC50: 4.5nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455855(CHEMBL4202601)
Affinity DataIC50: 5.60nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455851(CHEMBL4203540)
Affinity DataIC50: 8.30nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50455854(CHEMBL4203464)
Affinity DataIC50: 10nMAssay Description:Displacement of fluormone from human full length VDR after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed