Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50001229
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273013(CHEMBL4129456)
Affinity DataIC50: 3nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273116(CHEMBL4129805)
Affinity DataIC50: 8nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273012(CHEMBL4127600)
Affinity DataIC50: 11nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273111(CHEMBL4126041)
Affinity DataIC50: 22nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273082(CHEMBL4128079)
Affinity DataIC50: 30nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272971(CHEMBL4128782)
Affinity DataIC50: 33nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273048(CHEMBL4127190)
Affinity DataIC50: 37nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272972(CHEMBL4125756)
Affinity DataIC50: 49nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273050(CHEMBL4126989)
Affinity DataIC50: 52nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273084(CHEMBL4130214)
Affinity DataIC50: 160nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272977(CHEMBL4129002)
Affinity DataIC50: 200nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273049(CHEMBL4126938)
Affinity DataIC50: 210nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273083(CHEMBL4126435)
Affinity DataIC50: 280nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273011(CHEMBL4126528)
Affinity DataIC50: 390nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273000(CHEMBL4127992)
Affinity DataIC50: 440nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272970(CHEMBL4129133)
Affinity DataIC50: 500nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273010(CHEMBL4129913)
Affinity DataIC50: 560nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273081(CHEMBL4125839)
Affinity DataIC50: 660nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetShort transient receptor potential channel 6(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM21164(1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propo...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of mouse TRPC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273048(CHEMBL4127190)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273013(CHEMBL4129456)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273082(CHEMBL4128079)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50272977(CHEMBL4129002)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273116(CHEMBL4129805)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273048(CHEMBL4127190)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50272971(CHEMBL4128782)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273082(CHEMBL4128079)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272977(CHEMBL4129002)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50272972(CHEMBL4125756)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273010(CHEMBL4129913)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273050(CHEMBL4126989)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273000(CHEMBL4127992)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273011(CHEMBL4126528)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273050(CHEMBL4126989)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273083(CHEMBL4126435)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273111(CHEMBL4126041)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273000(CHEMBL4127992)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272971(CHEMBL4128782)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273013(CHEMBL4129456)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273084(CHEMBL4130214)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273049(CHEMBL4126938)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273111(CHEMBL4126041)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273116(CHEMBL4129805)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50272972(CHEMBL4125756)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273012(CHEMBL4127600)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273083(CHEMBL4126435)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273049(CHEMBL4126938)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50273010(CHEMBL4129913)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -80 mV holding potential after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50273084(CHEMBL4130214)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells at holding potential of -80 mV after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMed
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