Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50001623
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288363(CHEMBL4173216)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/V82I mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288363(CHEMBL4173216)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/I84V mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataEC50:  13nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/V82I mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288363(CHEMBL4173216)
Affinity DataEC50:  25nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288359(CHEMBL4164025)
Affinity DataEC50:  61nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288364(CHEMBL4160695)
Affinity DataEC50:  84nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288360(CHEMBL4163344)
Affinity DataEC50:  95nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataEC50:  112nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/I84V mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288356(CHEMBL4168317)
Affinity DataEC50:  165nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288362(CHEMBL4160405)
Affinity DataEC50:  226nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288365(CHEMBL4165197)
Affinity DataEC50:  309nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288345(CHEMBL4159139)
Affinity DataEC50:  678nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288347(CHEMBL4160986)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50180655(CHEBI:31781 | A-157378-0 | A-157378.0 | ABT-378 | ...)
Affinity DataEC50:  1.16E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM580(AG1776 | (4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2...)
Affinity DataEC50:  2.73E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed