Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with all data for entry = 50001473
TargetProtein kinase C delta type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  8.03E+3nMAssay Description:Activation of PKCdelta (unknown origin) expressed in human LNCAP cells harboring GFP-tagged RasGRP1 assessed as phosphorylation at ser299 residues af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50099066(phorbol 13-acetate 12-myristate | CHEMBL279115)
Affinity DataEC50:  82nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRAS guanyl-releasing protein 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  860nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  860nMAssay Description:Activation of RasGRP3 in human Ramos cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRAS guanyl-releasing protein 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  4.88E+3nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in HEK293 cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  6.09E+3nMAssay Description:Activation of RasGRP3 in human Ramos cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  8.28E+3nMAssay Description:Activation of PKCdelta (unknown origin) expressed in human LNCAP cells harboring GFP-tagged RasGRP3 assessed as phosphorylation at ser299 residues af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  1.83E+3nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRAS guanyl-releasing protein 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  970nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in human LNCAP cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  640nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in human LNCAP cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  1.69E+4nMAssay Description:Activation of PKCdelta (unknown origin) expressed in HEK293 cells harboring GFP-tagged RasGRP3 assessed as phosphorylation at ser299 residues after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  2.46E+4nMAssay Description:Activation of PKCdelta in human Ramos cells expressing RasGRP3 assessed as phosphorylation at ser299 residues after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  4.66E+3nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRAS guanyl-releasing protein 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  3.73E+3nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in human LNCAP cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  2.98E+3nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in human LNCAP cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50099066(phorbol 13-acetate 12-myristate | CHEMBL279115)
Affinity DataEC50:  290nMAssay Description:Activation of PKCdelta (unknown origin) expressed in HEK293 cells harboring GFP-tagged RasGRP3 assessed as phosphorylation at ser299 residues after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  1.26E+4nMAssay Description:Activation of PKCdelta (unknown origin) expressed in HEK293 cells harboring GFP-tagged RasGRP1 assessed as phosphorylation at ser299 residues after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280750(CHEMBL4160361)
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244449((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280765(CHEMBL4160647)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280759(CHEMBL4162516)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280768(CHEMBL4163130)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280751(CHEMBL4174397)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280773(CHEMBL4174723)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280756(CHEMBL4167589)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280771(CHEMBL4160540)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280752(CHEMBL4161221)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280757(CHEMBL4175934)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280750(CHEMBL4160361)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280758(CHEMBL4172461)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280754(CHEMBL4175128)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280772(CHEMBL4165117)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280745(CHEMBL4163809)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280753(CHEMBL4167900)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280763(CHEMBL4175761)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244856(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280755(CHEMBL4175333)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280746(CHEMBL4161062)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280764(CHEMBL4171253)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244451((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280769(CHEMBL4167264)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280756(CHEMBL4167589)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280758(CHEMBL4172461)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280751(CHEMBL4174397)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244798(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280757(CHEMBL4175934)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280767(CHEMBL4167457)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244644(rac-(E/Z)-(4-(4-(dimethylamino)benzylidene)-2-(hyd...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280759(CHEMBL4162516)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
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