Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50002717
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13664(3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxy-N-{[1-(...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13652(3-[2-(2,4-dichlorophenyl)ethoxy]-4-(methylsulfanyl...)
Affinity DataKi:  28nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13616(3-[2-(2,4-dichlorophenyl)ethoxy]-4-fluoro-N-{[1-(p...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13656(3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy-N-{...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13642(3-[2-(2,4-dichlorophenyl)ethoxy]-4-methyl-N-{[1-(p...)
Affinity DataKi:  55nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13651(5-[2-(2,4-dichlorophenyl)ethoxy]-1-N-{[1-(pyridin-...)
Affinity DataKi:  57nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13639(3-[2-(2,4-dichlorophenyl)ethoxy]-N-{[1-(pyridin-4-...)
Affinity DataKi:  106nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50462046(CHEMBL4227565)
Affinity DataKi:  241nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM13669(2-bromo-3-[2-(2,4-dichlorophenyl)ethoxy]-5-({[1-(p...)
Affinity DataKi:  285nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed