Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50003244
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468489(CHEMBL1305588)
Affinity DataIC50: 680nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468484(CHEMBL4288104)
Affinity DataIC50: 850nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 880nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468485(CHEMBL4286850)
Affinity DataIC50: 940nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468490(CHEMBL4291398)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468486(CHEMBL4281274)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468482(CHEMBL4291890)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468480(CHEMBL4282332)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468479(CHEMBL4280810)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50015825(CHEMBL73133 | Methyl-[1,2,4]triazolo[4,3-a]quinoxa...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468483(CHEMBL4288069)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468488(CHEMBL4290204)
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468481(CHEMBL4276735)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50468487(CHEMBL4284675)
Affinity DataIC50: 5.38E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed