Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50001478
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50228465(BMS-488043 | 1-(4-benzoylpiperazin-1-yl)-2-(4,7-di...)
Affinity DataKd:  19nMAssay Description:Inhibition of [3H]BMS-488043 binding to HIV-1 JRFL gp120 after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50236759(BMS-626529 | Temsavir)
Affinity DataKd:  0.830nMAssay Description:Inhibition of [3H]BMS-488043 binding to HIV-1 JRFL gp120 after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50236759(BMS-626529 | Temsavir)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50236759(BMS-626529 | Temsavir)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50236759(BMS-626529 | Temsavir)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50236759(BMS-626529 | Temsavir)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50255106(CHEMBL4104608)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed