Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50002371
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataKd:  2.18E+3nMAssay Description:Binding affinity to MMP9 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50323212(CHEMBL63677 | 6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50323196(4'-methylamentoflavone | bilobetin | CHEMBL378188)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50323212(CHEMBL63677 | 6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457771(CHEMBL4206592)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457774(CHEMBL4206956)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457777(CHEMBL4216342)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457775(CHEMBL451902 | Robustaflavone-4''-Methyl Ether)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457776(CHEMBL4208646)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457777(CHEMBL4216342)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457772(CHEMBL4211480)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457775(CHEMBL451902 | Robustaflavone-4''-Methyl Ether)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457778(CHEMBL4213048)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457772(CHEMBL4211480)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457776(CHEMBL4208646)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457771(CHEMBL4206592)
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457773(CHEMBL4208066)
Affinity DataIC50: 5.42E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457773(CHEMBL4208066)
Affinity DataIC50: 6.61E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457776(CHEMBL4208646)
Affinity DataIC50: 7.43E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457772(CHEMBL4211480)
Affinity DataIC50: 8.12E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataIC50: 8.26E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50093523(CHEMBL3585679 | PTP1B spring 6 (6))
Affinity DataIC50: 8.54E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457771(CHEMBL4206592)
Affinity DataIC50: 8.78E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457774(CHEMBL4206956)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457775(CHEMBL451902 | Robustaflavone-4''-Methyl Ether)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50323196(4'-methylamentoflavone | bilobetin | CHEMBL378188)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457774(CHEMBL4206956)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457778(CHEMBL4213048)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457773(CHEMBL4208066)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50323196(4'-methylamentoflavone | bilobetin | CHEMBL378188)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed