Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50002254
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50207816(N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021078(CHEMBL286728 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021085(CHEMBL444281 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021086(CHEMBL422937 | N-(8-Amino-octyl)-2-[4-(2,6-dioxo-1...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021077(CHEMBL27043 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50018002([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021087(CHEMBL441598 | 2-[4-(1,3-Dimethyl-2,6-dioxo-2,3,6,...)
Affinity DataKi:  20nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021083(CHEMBL265739 | N-(2-Acetylamino-ethyl)-2-[4-(2,6-d...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021087(CHEMBL441598 | 2-[4-(1,3-Dimethyl-2,6-dioxo-2,3,6,...)
Affinity DataKi:  26nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50018419([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  30nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021088(CHEMBL286063 | [4-(2,6-Dioxo-1,3-dipropyl-2,3,6,9-...)
Affinity DataKi:  32nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021079(CHEMBL27028 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,9...)
Affinity DataKi:  32nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50008405(CHEMBL27041 | 2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7...)
Affinity DataKi:  34nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021080(2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...)
Affinity DataKi:  36nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50018002([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  40nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50018419([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  42nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021077(CHEMBL27043 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7...)
Affinity DataKi:  47nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50207816(N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3...)
Affinity DataKi:  49nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM82012(8-(4-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  50nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(8-(4-Hydroxy-phenyl)-1,3-dipropyl-3,9-dihydro-puri...)
Affinity DataKi:  50nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021081(CHEMBL283628 | 5-(2-Oxo-hexahydro-thieno[3,4-d]imi...)
Affinity DataKi:  54nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50008405(CHEMBL27041 | 2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7...)
Affinity DataKi:  58nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021088(CHEMBL286063 | [4-(2,6-Dioxo-1,3-dipropyl-2,3,6,9-...)
Affinity DataKi:  59nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021085(CHEMBL444281 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  62nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021083(CHEMBL265739 | N-(2-Acetylamino-ethyl)-2-[4-(2,6-d...)
Affinity DataKi:  62nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021079(CHEMBL27028 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,9...)
Affinity DataKi:  68nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021082(CHEMBL286493 | 1,3-Dicyclohexyl-1-{2-[4-(2,6-dioxo...)
Affinity DataKi:  96nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM82012(8-(4-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  130nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021081(CHEMBL283628 | 5-(2-Oxo-hexahydro-thieno[3,4-d]imi...)
Affinity DataKi:  180nMAssay Description:Binding affinity against A2 adenosine receptor in [3H]adenine-labeled guinea pig cerebral cortical slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021078(CHEMBL286728 | 2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,...)
Affinity DataKi:  320nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021084(CHEMBL285103 | [4-(1,3-Dimethyl-2,6-dioxo-2,3,6,9-...)
Affinity DataKi:  430nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021086(CHEMBL422937 | N-(8-Amino-octyl)-2-[4-(2,6-dioxo-1...)
Affinity DataKi:  470nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021084(CHEMBL285103 | [4-(1,3-Dimethyl-2,6-dioxo-2,3,6,9-...)
Affinity DataKi:  500nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021080(2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...)
Affinity DataKi:  750nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50021082(CHEMBL286493 | 1,3-Dicyclohexyl-1-{2-[4-(2,6-dioxo...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed