Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50012633
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at recombinant human PPARgamma LBD (205 to 505 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50558882(CHEMBL4451056)
Affinity DataEC50:  8.50E+3nMAssay Description:Agonist activity at recombinant human PPARgamma LBD (205 to 505 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50558883(CHEMBL4522023)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at recombinant human PPARgamma LBD (205 to 505 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50558883(CHEMBL4522023)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50558882(CHEMBL4451056)
Affinity DataEC50:  2.60E+4nMAssay Description:Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | Hexadecanoic acid anion | H...)
Affinity DataEC50:  3.50E+4nMAssay Description:Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  3.90E+4nMAssay Description:Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)