Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002781
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462910(CHEMBL4247870)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462909(CHEMBL4243975)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462907(CHEMBL4247474)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462908(CHEMBL4251213)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462907(CHEMBL4247474)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M mutant (695-end residues) expressed in baculovirus infected Sf9 cells using poly (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781-end residues) expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462908(CHEMBL4251213)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M mutant (695-end residues) expressed in baculovirus infected Sf9 cells using poly (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462909(CHEMBL4243975)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M mutant (695-end residues) expressed in baculovirus infected Sf9 cells using poly (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462910(CHEMBL4247870)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M mutant (695-end residues) expressed in baculovirus infected Sf9 cells using poly (4:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462909(CHEMBL4243975)
Affinity DataIC50: 196nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781-end residues) expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462910(CHEMBL4247870)
Affinity DataIC50: 496nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781-end residues) expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462907(CHEMBL4247474)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781-end residues) expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50462908(CHEMBL4251213)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781-end residues) expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed