Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50007128
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human His-tagged p110beta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368687(US10227350, Compound 102)
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human His-tagged p110beta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 42nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 43nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368687(US10227350, Compound 102)
Affinity DataIC50: 67nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 188nMAssay Description:Inhibition of full length human p110alpha/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 188nMAssay Description:Inhibition of full length human p110alpha/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368687(US10227350, Compound 102)
Affinity DataIC50: 233nMAssay Description:Inhibition of full length human p110alpha/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368687(US10227350, Compound 102)
Affinity DataIC50: 440nMAssay Description:Inhibition of full length human PI3Kgamma using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of full length human His-tagged p110beta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of full length human His-tagged p110beta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of full length human PI3Kgamma using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of full length human PI3Kgamma using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human PI3Kgamma using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM368657(US10227350, Compound 106 | US10227350, Compound 10...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human p110alpha/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed