Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50001766
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0730nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human PRB expressed in African green monkey CV1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human GR assessed as reduction in dexamethasone-induced transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human AR assessed as reduction in DHT-induced transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human PRB expressed in African green monkey CV1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367097(CHEMBL4173799)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367121(CHEMBL4175249)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50203153(CHEMBL3927163)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50355243(CHEMBL1835836)
Affinity DataIC50: 123nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367113(CHEMBL4174942)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367063(CHEMBL4174199)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367097(CHEMBL4173799)
Affinity DataIC50: 150nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367116(CHEMBL4167377)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367115(CHEMBL4171805)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367126(CHEMBL4163497)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367097(CHEMBL4173799)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367118(CHEMBL4160128)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396595(CHEMBL2171906)
Affinity DataIC50: 340nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367121(CHEMBL4175249)
Affinity DataIC50: 340nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367120(CHEMBL4163940)
Affinity DataIC50: 360nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012248(CHEMBL1765167)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012268(CHEMBL1765172)
Affinity DataIC50: 560nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367122(CHEMBL4164293)
Affinity DataIC50: 730nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012269(CHEMBL3259994)
Affinity DataIC50: 780nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367119(CHEMBL4170774)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367117(CHEMBL1765173)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012260(CHEMBL1091939)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human AR assessed as reduction in DHT-induced transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012270(CHEMBL1093517)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367063(CHEMBL4174199)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PGR LBD (678 to 933 residues) expressed in baculovirus-infected insect cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367121(CHEMBL4175249)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human GR assessed as reduction in dexamethasone-induced transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012279(CHEMBL1091940)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012238(CHEMBL1765175)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012265(CHEMBL3259996)
Affinity DataIC50: 3.80E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367114(CHEMBL1765165)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012273(CHEMBL1765174)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012261(CHEMBL1093016)
Affinity DataIC50: 7.10E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012239(CHEMBL1092222)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012267(CHEMBL1093312)
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012264(CHEMBL1089421)
Affinity DataIC50: 8.30E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012272(CHEMBL1088840)
Affinity DataIC50: 8.60E+3nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50012271(CHEMBL1093421)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367127(CHEMBL1765166)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367063(CHEMBL4174199)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human CMX-AR expressed in HEK293 cells assessed as reduction in dihydrotestosterone-induced transactivation activity after 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367063(CHEMBL4174199)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human GAL4N-fused LXRbeta LBD expressed in HEK293 cells assessed as reduction in T0901317-induced transactivation activity aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367063(CHEMBL4174199)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human CMX-GRalpha expressed in HEK293 cells assessed as reduction in dexamethasone-induced transactivation activity after 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367121(CHEMBL4175249)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human CMX-GRalpha expressed in HEK293 cells assessed as reduction in dexamethasone-induced transactivation activity after 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50367121(CHEMBL4175249)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human GAL4N-fused LXRalpha LBD expressed in HEK293 cells assessed as reduction in T0901317-induced transactivation activity af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
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