Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50003113
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 4nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467111(CHEMBL4281659)
Affinity DataIC50: 6nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 8nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467109(CHEMBL4292295)
Affinity DataIC50: 10nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 44nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467111(CHEMBL4281659)
Affinity DataIC50: 45nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 80nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 110nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467111(CHEMBL4281659)
Affinity DataIC50: 130nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 150nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467111(CHEMBL4281659)
Affinity DataIC50: 150nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467109(CHEMBL4292295)
Affinity DataIC50: 160nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 370nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 570nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467109(CHEMBL4292295)
Affinity DataIC50: 610nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467109(CHEMBL4292295)
Affinity DataIC50: 970nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50403016(CHEMBL2207845)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467112(CHEMBL4287557)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467113(CHEMBL4285090)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed