Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50003292
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 50nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 90nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469124(CHEMBL113332)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50: 170nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469124(CHEMBL113332)
Affinity DataIC50: 232nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 316nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469121(CHEMBL1210876)
Affinity DataIC50: 340nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 350nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 625nMAssay Description:Displacement of Fluormone-DHT from rat GST-tagged rat AR LBD expressed in insect cells after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469123(CHEMBL1210878)
Affinity DataIC50: 730nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469123(CHEMBL1210878)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469121(CHEMBL1210876)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469125(CHEMBL1210959)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469126(CHEMBL1210880)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469124(CHEMBL113332)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469123(CHEMBL1210878)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469126(CHEMBL1210880)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469121(CHEMBL1210876)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed