Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50003302
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469211(CHEMBL4283503)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50466158(CHEMBL4290247)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469213(CHEMBL4278353)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469215(CHEMBL4281810)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469214(CHEMBL4292442)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469218(CHEMBL4287985)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469211(CHEMBL4283503)
Affinity DataIC50: 43nMAssay Description:Inhibition of DYRK1A in human HeLa cells harboring GFP-SF3b1-NT assessed as reduction in SF3b1 phosphorylation at T343 residue after 18 hrs by Wester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469217(CHEMBL4294080)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469214(CHEMBL4292442)
Affinity DataIC50: 67nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469211(CHEMBL4283503)
Affinity DataIC50: 73nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469211(CHEMBL4283503)
Affinity DataIC50: 76nMAssay Description:Inhibition of human GST-tagged haspin expressed in baculovirus expression system in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469210(CHEMBL4287083)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469210(CHEMBL4287083)
Affinity DataIC50: 99nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50466161(CHEMBL4281037)
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469212(CHEMBL4290268)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469216(CHEMBL4290096)
Affinity DataIC50: 132nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469213(CHEMBL4278353)
Affinity DataIC50: 138nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469217(CHEMBL4294080)
Affinity DataIC50: 219nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in baculovirus expression system using KKISGRLSPIMTEQ-NH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50469211(CHEMBL4283503)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human GST-tagged CLK1 (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substrate after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50466160(CHEMBL4280981)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed