Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50002535
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50138406([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-o...)
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459813(CHEMBL4205384)
Affinity DataIC50: 114nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459816(CHEMBL518606)
Affinity DataIC50: 263nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459815(CHEMBL4216055)
Affinity DataIC50: 324nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459812(CHEMBL4214561)
Affinity DataIC50: 444nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459817(CHEMBL4211088)
Affinity DataIC50: 523nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459814(CHEMBL4211602)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Idenix An Msd

Curated by ChEMBL
LigandPNGBDBM50459811(CHEMBL4206712)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed