Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50007155
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506775(CHEMBL4593437)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506777(CHEMBL4476057)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506780(CHEMBL4550522)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506778(CHEMBL4469596)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506779(CHEMBL4521590)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506781(CHEMBL4435005)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human HDAC6 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506775(CHEMBL4593437)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506780(CHEMBL4550522)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506781(CHEMBL4435005)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506779(CHEMBL4521590)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506778(CHEMBL4469596)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506784(CHEMBL4527662)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506777(CHEMBL4476057)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human HDAC1 using RHK-K(Ac) as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506776(CHEMBL4442279)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506780(CHEMBL4550522)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506786(CHEMBL4469152)
Affinity DataEC50:  4.60E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506774(CHEMBL4470149)
Affinity DataEC50:  4.80E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506789(CHEMBL4470318)
Affinity DataEC50:  5.10E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506782(CHEMBL4461581)
Affinity DataEC50:  5.20E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506788(CHEMBL4526979)
Affinity DataEC50:  5.40E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506783(CHEMBL4582042)
Affinity DataEC50:  5.40E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506790(CHEMBL4574840)
Affinity DataEC50:  5.40E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506785(CHEMBL4537137)
Affinity DataEC50:  6.20E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506787(CHEMBL4558658)
Affinity DataEC50:  8.70E+3nMAssay Description:Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506781(CHEMBL4435005)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506782(CHEMBL4461581)
Affinity DataEC50:  3.18E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506777(CHEMBL4476057)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506779(CHEMBL4521590)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506775(CHEMBL4593437)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506778(CHEMBL4469596)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by homogeneous fluorescence release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506774(CHEMBL4470149)
Affinity DataEC50:  5.09E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506776(CHEMBL4442279)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506789(CHEMBL4470318)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506787(CHEMBL4558658)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506785(CHEMBL4537137)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506784(CHEMBL4527662)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506783(CHEMBL4582042)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506786(CHEMBL4469152)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506785(CHEMBL4537137)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506782(CHEMBL4461581)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506774(CHEMBL4470149)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506784(CHEMBL4527662)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506790(CHEMBL4574840)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506788(CHEMBL4526979)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50506787(CHEMBL4558658)
Affinity DataEC50:  1.37E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed