Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50003211
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50246899(N-{[(1S)-1-carboxy-5-{[(4-iodophenyl)carbonyl]amin...)
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468173(CHEMBL4284995)
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468167(CHEMBL4280968)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468163(CHEMBL4286872)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468164(CHEMBL4288368)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468174(CHEMBL4277729)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468175(CHEMBL4291782)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468177(CHEMBL4291245)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468178(CHEMBL4283406)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468180(CHEMBL4294773)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468170(CHEMBL4292853)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468168(CHEMBL4291603)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468169(CHEMBL4281573)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468172(CHEMBL4289458)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468171(CHEMBL4294649)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468179(CHEMBL4279502)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468162(CHEMBL4286751)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468165(CHEMBL4281157)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468176(CHEMBL4279929)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50468166(CHEMBL4287838)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed