Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50008612
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520826(CHEMBL4545086)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520826(CHEMBL4545086)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520827(CHEMBL4536146)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520827(CHEMBL4536146)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520828(CHEMBL4575647)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520828(CHEMBL4575647)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520826(CHEMBL4545086)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520828(CHEMBL4575647)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520827(CHEMBL4536146)
Affinity DataIC50: 2.77E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed