Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50006824
TargetProteasome subunit beta type-5(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50: 420nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50: 440nMAssay Description:Inhibition of 20s immunoproteasome LMP2 in human erythrocytes using Ac-Pro-Ala-Leu-MCA as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50: 480nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50: 630nMAssay Description:Inhibition of 20s immunoproteasome LMP7 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 20s immunoproteasome LMP2 in human erythrocytes using Ac-Pro-Ala-Leu-MCA as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 20s immunoproteasome LMP7 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503684(CHEMBL4458350)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta2 trypsin-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 20s immunoproteasome MECL1 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed