Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50008632
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521005(CHEMBL4553651)
Affinity DataIC50: 560nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521009(CHEMBL4562198)
Affinity DataIC50: 670nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521011(CHEMBL4475678)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521001(CHEMBL4552250)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521009(CHEMBL4562198)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521006(CHEMBL4520323)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521005(CHEMBL4553651)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520998(CHEMBL4463164)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521004(CHEMBL4474151)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521003(CHEMBL4440350)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520995(CHEMBL4439936)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521000(CHEMBL4554367)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520997(CHEMBL4524631)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521000(CHEMBL4554367)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521002(CHEMBL4516540)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521006(CHEMBL4520323)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521005(CHEMBL4553651)
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521003(CHEMBL4440350)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520996(CHEMBL4467746)
Affinity DataIC50: 5.47E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521001(CHEMBL4552250)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521004(CHEMBL4474151)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of human amyloid beta (1 to 42) self-induced aggregation after 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521011(CHEMBL4475678)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521007(CHEMBL4451935)
Affinity DataIC50: 6.75E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521004(CHEMBL4474151)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521002(CHEMBL4516540)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520995(CHEMBL4439936)
Affinity DataIC50: 9.21E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 9.87E+3nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521011(CHEMBL4475678)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521000(CHEMBL4554367)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520997(CHEMBL4524631)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521009(CHEMBL4562198)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521003(CHEMBL4440350)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521001(CHEMBL4552250)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521010(CHEMBL4527242)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520997(CHEMBL4524631)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520995(CHEMBL4439936)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521004(CHEMBL4474151)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521006(CHEMBL4520323)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50521002(CHEMBL4516540)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50520998(CHEMBL4463164)
Affinity DataIC50: 2.74E+4nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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