Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50003034
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to wild-type human partial length RIPK2 (M1 to K310 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataKd:  7.20E+3nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 4(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to wild-type human partial length RIPK4 (M1 to V303 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human TrkC (510 to end residues) using GEEPLYWSFPAKK as substrate after 40 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human TrkB (455 to end residues) using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33P]-ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466055(CHEMBL4279118)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466049(CHEMBL4292454)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466048(CHEMBL4290735)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466042(CHEMBL4290948)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466059(CHEMBL4289355)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466067(CHEMBL4285969)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466043(CHEMBL4292027)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human Flt4 V1128L/H1146R double mutant (800 to end residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human TrkA (440 to end residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466036(CHEMBL4289802)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HRI (140 to end residues) using RSRSRSRSRSRSR as substrate after 120 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466064(CHEMBL4283766)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human Mer H628Q/R794A double mutant (557 to 882 residues) using GGMEDIYFEFMGG as substrate after 40 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466039(CHEMBL4292726)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human Axl Q764R mutant (473 to end residues) using KKSRGDYMTMQIG as substrate after 40 mins in presence of [gamma-33P]-ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human DDR1 (492 to end residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant full length human MAP4K5 using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant full length human Lck using KVEKIGEGTYGVV as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466057(CHEMBL4278044)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466066(CHEMBL4290430)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human MST2 (2 to end residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 10(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human MLK2 (1 to 449 residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human MLK1 (134 to 414 residues) using casein as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466040(CHEMBL4283246)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466056(CHEMBL4289381)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human Itk (352 to 617 residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466045(CHEMBL4281501)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human Ret (658 to ed residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human Tie2 Q939H/Q940H double mutant (771 to end residues) using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human Flt1 (783 to end residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466047(CHEMBL4291229)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466041(CHEMBL4287016)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant full length human Lyn using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human FAK (411 to 686 residues) using EEEEYEEEEEEYY as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human Met A1209G/V1290L double mutant (974 to end residues) using KKKGQEEEYVFIE as substrate after 40 mins in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466062(CHEMBL4279092)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase WNK3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human WNK3 (1 to 434 residues) using myelin basic protein as substrate after 40 mins in presence of [gamma-33P]-ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466063(CHEMBL4289311)
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant human MAP4K3 (1 to 291 residues) using RLGRDKYKTLRQI as substrate after 40 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466060(CHEMBL4285949)
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 111nMAssay Description:Inhibition of recombinant full length human BRK using poly(Glu, Tyr) 4:1 as substrate after 40 mins in presence of [gamma-33P]-ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human DDR2 S642A mutant (467 to end residues) using KKSRGDYMTMQIG as substrate after 40 mins in presence of [gamma-33P]-ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Sichuan University/Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50466065(CHEMBL4282588)
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human RIPK1 (8 to 322 residues) using myelin basic protein as substrate after 120 mins in presence of [gamma-33P]-ATP by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
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