Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50008336
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518237(CHEMBL4552529)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518228(CHEMBL4445920)
Affinity DataIC50: 72nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518224(CHEMBL4570769)
Affinity DataIC50: 89nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518223(CHEMBL4529354)
Affinity DataIC50: 116nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518225(CHEMBL4434898)
Affinity DataIC50: 177nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518217(CHEMBL4544782)
Affinity DataIC50: 218nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518232(CHEMBL4460740)
Affinity DataIC50: 224nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518220(CHEMBL4540726)
Affinity DataIC50: 284nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518234(CHEMBL4516390)
Affinity DataIC50: 290nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518227(CHEMBL4452377)
Affinity DataIC50: 350nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518233(CHEMBL4526365)
Affinity DataIC50: 443nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518226(CHEMBL4534674)
Affinity DataIC50: 514nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518230(CHEMBL4453311)
Affinity DataIC50: 525nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518221(CHEMBL4450878)
Affinity DataIC50: 555nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518218(CHEMBL4567109)
Affinity DataIC50: 775nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518229(CHEMBL4558761)
Affinity DataIC50: 946nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518236(CHEMBL4469064)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518231(GNF-Pf-4180 | MMV006169 | CHEMBL597248)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518235(CHEMBL4525521)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518222(CHEMBL4552918)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518219(CHEMBL4565213)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed