Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50008347
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM32362(cid_11617559 | GW-2580 | 5-[[3-methoxy-4-[(4-metho...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518405(CHEMBL4462286)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518399(CHEMBL4552261)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518415(CHEMBL4436822)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518403(CHEMBL4448250)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518413(CHEMBL4519682)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518410(CHEMBL4446254)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518409(CHEMBL4446242)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518402(CHEMBL4532017)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518401(CHEMBL4438472)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518414(CHEMBL4439265)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518407(CHEMBL4520105)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518412(CHEMBL4454323)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518406(CHEMBL4455645)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518400(CHEMBL4447898)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518411(CHEMBL4580020)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DDR2 (467 to end residues) expressed in baculovirus infected Sf21 insect cells using Axltide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged c-RAF Y340D/Y341D double mutant (306 to 648 residues) expressed in baculovirus infected Sf21 in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR1 (456 to 765 residues) expressed in baculovirus infected Sf21 insect cells using IGF-IRtid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged Tie2 (771 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 258nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MELK (1 to 340 residues) expressed in baculovirus infected Sf21 insect cells using KKLNRTLSFAEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 310nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 527nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells using MBP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed