Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50008386
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518668(CHEMBL4546569)
Affinity DataIC50: 32nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518676(CHEMBL4453888)
Affinity DataIC50: 94nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518675(CHEMBL4458898)
Affinity DataIC50: 280nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518679(CHEMBL4468962)
Affinity DataIC50: 640nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518673(CHEMBL4448964)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518665(CHEMBL4445587)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518667(CHEMBL4585746)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518661(CHEMBL4554148)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518666(CHEMBL4556590)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518671(CHEMBL4560122)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518680(CHEMBL4573946)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518677(CHEMBL4467680)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518664(CHEMBL4473863)
Affinity DataIC50: 5.41E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518678(CHEMBL4516802)
Affinity DataIC50: 6.38E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518662(CHEMBL4436938)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518663(CHEMBL4551589)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518670(CHEMBL4568207)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518669(CHEMBL4517057)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518672(CHEMBL4594032)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSolute carrier family 22 member 12(Human)
Tianjin Medical University

Curated by ChEMBL
LigandPNGBDBM50518674(CHEMBL4459618)
Affinity DataIC50: 3.65E+5nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as reduction in [8-14C]uric acid uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed