Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50008387
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM8125(Darunavir (DRV) | CHEMBL1323 | (3R,3aS,6aR)-hexahy...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518684(CHEMBL4448278)
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518687(CHEMBL4530869)
Affinity DataIC50: 150nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518700(CHEMBL4444407)
Affinity DataIC50: 150nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518701(CHEMBL4443902)
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518686(CHEMBL4444031)
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518690(CHEMBL4561381)
Affinity DataIC50: 210nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518688(CHEMBL4447543)
Affinity DataIC50: 220nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518685(CHEMBL4452115)
Affinity DataIC50: 240nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518699(CHEMBL4541253)
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518682(CHEMBL4566224)
Affinity DataIC50: 370nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518694(CHEMBL4555048)
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518683(CHEMBL4451344)
Affinity DataIC50: 460nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518692(CHEMBL4549913)
Affinity DataIC50: 480nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518695(CHEMBL4556761)
Affinity DataIC50: 490nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518693(CHEMBL4579986)
Affinity DataIC50: 500nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518698(CHEMBL4443043)
Affinity DataIC50: 580nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518697(CHEMBL4453560)
Affinity DataIC50: 610nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518696(CHEMBL4473528)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518681(CHEMBL4455767)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518691(CHEMBL4454556)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50518689(CHEMBL4459161)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed