Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50007287
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508165(CHEMBL4592343)
Affinity DataIC50: 19nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508167(CHEMBL4469267)
Affinity DataIC50: 28nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508161(CHEMBL4579774)
Affinity DataIC50: 28nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 35nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 74nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataIC50: 230nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508161(CHEMBL4579774)
Affinity DataIC50: 230nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508167(CHEMBL4469267)
Affinity DataIC50: 240nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508165(CHEMBL4592343)
Affinity DataIC50: 250nMAssay Description:Inhibition of FAM-Bid peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508165(CHEMBL4592343)
Affinity DataIC50: 281nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508167(CHEMBL4469267)
Affinity DataIC50: 665nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508161(CHEMBL4579774)
Affinity DataIC50: 847nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508166(CHEMBL4559296)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508166(CHEMBL4559296)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508163(CHEMBL4438858)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508164(CHEMBL4476315)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508163(CHEMBL4438858)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508162(CHEMBL4442030)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508164(CHEMBL4476315)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wuhan Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50508162(CHEMBL4442030)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed