Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50009561
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(SMR000058550 | MLS000069510 | 3-[2-[4-[bis(4-fluor...)
Affinity DataIC50: 300nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(SMR000058550 | MLS000069510 | 3-[2-[4-[bis(4-fluor...)
Affinity DataIC50: 300nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Pig)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529936(CHEMBL4558937)
Affinity DataIC50: 600nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Pig)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529936(CHEMBL4558937)
Affinity DataIC50: 600nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529933(CHEMBL1494303)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529933(CHEMBL1494303)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(SMR000058550 | MLS000069510 | 3-[2-[4-[bis(4-fluor...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(SMR000058550 | MLS000069510 | 3-[2-[4-[bis(4-fluor...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Pig)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(SMR000058550 | MLS000069510 | 3-[2-[4-[bis(4-fluor...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Pig)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM43868(SMR000058550 | MLS000069510 | 3-[2-[4-[bis(4-fluor...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Rat)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat FLAG-tagged DGKalpha expressed in HEK293T cells using DAG as substrate measured after 15 mins in presence of [gamma-32P]ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Rat)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat FLAG-tagged DGKalpha expressed in HEK293T cells using DAG as substrate measured after 15 mins in presence of [gamma-32P]ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Pig)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Pig)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50001775(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529935(COCHLIOQUINONE A)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529935(COCHLIOQUINONE A)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529932(STEMPHONE)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529932(STEMPHONE)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529934(ETHYLENE GLYCOL DIOCTANOATE)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529934(ETHYLENE GLYCOL DIOCTANOATE)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529937(CHEBI:75342 | Glyceryl monooleate)
Affinity DataKi:  9.10E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDiacylglycerol kinase alpha(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529937(CHEBI:75342 | Glyceryl monooleate)
Affinity DataKi:  9.10E+4nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed