Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50008277
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517327(CHEMBL4472928)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517320(CHEMBL4568153)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50320463(H-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH | D[CFWKYC]V ...)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517312(CHEMBL4526244)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517323(CHEMBL4474481)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50445383(CHEMBL3104471)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517325(CHEMBL4590360)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517314(Urotensin-II)
Affinity DataEC50:  3nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517314(Urotensin-II)
Affinity DataEC50:  3nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517320(CHEMBL4568153)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517315(CHEMBL4454498)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517316(CHEMBL4462940)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517320(CHEMBL4568153)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517325(CHEMBL4590360)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50320463(H-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH | D[CFWKYC]V ...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517315(CHEMBL4454498)
Affinity DataEC50:  4.70nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517327(CHEMBL4472928)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517315(CHEMBL4454498)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517316(CHEMBL4462940)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50320463(H-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH | D[CFWKYC]V ...)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517317(CHEMBL4475783)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517317(CHEMBL4475783)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50445383(CHEMBL3104471)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517314(Urotensin-II)
Affinity DataKi:  7.80nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50445383(CHEMBL3104471)
Affinity DataEC50:  7.80nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517316(CHEMBL4462940)
Affinity DataEC50:  9.5nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517324(CHEMBL4449844)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517312(CHEMBL4526244)
Affinity DataEC50:  14nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517321(CHEMBL4568539)
Affinity DataEC50:  19nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517317(CHEMBL4475783)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517318(CHEMBL4467241)
Affinity DataEC50:  22nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517323(CHEMBL4474481)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517323(CHEMBL4474481)
Affinity DataEC50:  25nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517324(CHEMBL4449844)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517312(CHEMBL4526244)
Affinity DataEC50:  83nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517322(CHEMBL4447811)
Affinity DataEC50:  105nMAssay Description:Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517318(CHEMBL4467241)
Affinity DataEC50:  200nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517321(CHEMBL4568539)
Affinity DataKi:  229nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517322(CHEMBL4447811)
Affinity DataKi:  245nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517321(CHEMBL4568539)
Affinity DataEC50:  537nMAssay Description:Agonist activity at urotensin 2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contraction relative to KCl-induced cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517318(CHEMBL4467241)
Affinity DataKi:  813nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517313(CHEMBL4483461)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517326(CHEMBL4549818)
Affinity DataKi:  2.09E+3nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517330(CHEMBL4455086)
Affinity DataKi:  2.14E+3nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517329(CHEMBL4565187)
Affinity DataKi:  5.37E+3nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517328(CHEMBL4540501)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50517319(CHEMBL4544618)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [125I]-URP or human [125I[-urotensin-2 from human urotensin 2 receptor expressed in HEK293 or CHOK1 cells after 2 hrs by gamma-counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed