Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50009569
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50530006(CHEMBL4515606)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50530006(CHEMBL4515606)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human 5-LOX expressed in Escherichia coli using arachidonic acid as substrate by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50131688(4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol | Pteros...)
Affinity DataIC50: 9.32E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50131688(4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol | Pteros...)
Affinity DataIC50: 9.32E+3nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50505498(CHEBI:31687 | Idebenone | Raxone)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108046((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Vellore Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50108046((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate measured after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed