Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50008683
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521286(CHEMBL4450214)
Affinity DataEC50:  2.43E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521287(CHEMBL4448132)
Affinity DataEC50:  890nMAssay Description:Activation of human homomeric KCNQ4 expressed in CHOK1 cells at -10 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521288(CHEMBL4438770)
Affinity DataEC50:  1.42E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521289(CHEMBL4588394)
Affinity DataEC50:  1.68E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521289(CHEMBL4588394)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat KCNQ2 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521288(CHEMBL4438770)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat KCNQ2 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521286(CHEMBL4450214)
Affinity DataEC50:  2.03E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521286(CHEMBL4450214)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat KCNQ2 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521289(CHEMBL4588394)
Affinity DataEC50:  780nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | N-(2-amino-4-(4-fluorobenzylamino)-p...)
Affinity DataEC50:  2.17E+3nMAssay Description:Agonist activity at rat KCNQ2 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily KQT member 5(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50521288(CHEMBL4438770)
Affinity DataEC50:  1.37E+3nMAssay Description:Agonist activity at human KCNQ5 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed