Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50009758
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 600nMAssay Description:Inhibition of DNMT1 (unknown origin) using biotinylated substrate using [3H]-SAM after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM11979(MgrA inhibitor, 1 | CHEMBL115145 | 5-[(3-carboxy-4...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of DNMT3A/3L (unknown origin) using poly(2'-deoxyinosinic-2'-deoxycytidylic acid) as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like/3B(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM11979(MgrA inhibitor, 1 | CHEMBL115145 | 5-[(3-carboxy-4...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of DNMT3B/3L (unknown origin) using poly(2'-deoxyinosinic-2'-deoxycytidylic acid) as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM11979(MgrA inhibitor, 1 | CHEMBL115145 | 5-[(3-carboxy-4...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of DNMT1 (unknown origin) using biotinylated substrate using [3H]-SAM after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed