Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50008302
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 60nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517778(CHEMBL4447196)
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517776(CHEMBL4449599)
Affinity DataIC50: 540nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517774(CHEMBL4462971)
Affinity DataIC50: 700nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517771(CHEMBL4585048)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517773(CHEMBL4588486)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517777(CHEMBL4464785)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517776(CHEMBL4449599)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517770(CHEMBL4474429)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517775(CHEMBL4540070)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517772(CHEMBL4568408)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed