Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50007525
TargetCholinesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM47353(US9687494, 25 | BDBM143220 | US9029362, 173)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human BACE1 preincubated with enzyme for 20 mins followed by addition of Rh-EVNLDAEFK-Quencher as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50510135(CHEMBL4554770)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human BACE1 preincubated with enzyme for 20 mins followed by addition of Rh-EVNLDAEFK-Quencher as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50510134(CHEMBL4458644)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human BACE1 preincubated with enzyme for 20 mins followed by addition of Rh-EVNLDAEFK-Quencher as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50510136(CHEMBL4532096)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human BACE1 preincubated with enzyme for 20 mins followed by addition of Rh-EVNLDAEFK-Quencher as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50510137(CHEMBL4574899)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human BACE1 preincubated with enzyme for 20 mins followed by addition of Rh-EVNLDAEFK-Quencher as substrate measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed