Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50013242
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of human recombinant GST-tagged PARP-1 expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP-2 expressed in Baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563975(CHEMBL4799284)
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of human recombinant GST-tagged PARP-1 expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563977(CHEMBL4797518)
Affinity DataIC50: 5.83E+4nMAssay Description:Inhibition of human recombinant GST-tagged PARP-1 expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563976(CHEMBL4786454)
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of human recombinant GST-tagged PARP-1 expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563974(CHEMBL4797458)
Affinity DataIC50: 2.54E+5nMAssay Description:Inhibition of human recombinant GST-tagged PARP-1 expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563974(CHEMBL4797458)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP-2 expressed in Baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563975(CHEMBL4799284)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP-2 expressed in Baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563976(CHEMBL4786454)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP-2 expressed in Baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563977(CHEMBL4797518)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP-2 expressed in Baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed