Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 50022617
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of JAK1 in human TF-1 cells assessed as reduction in OSM-induced STAT3 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2nMAssay Description:Inhibition of JAK1/JAK3 in human HEKa cells assessed as reduction in IL-4-induced STAT6 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human JAK1 (845 to 1142 residues) expressed in Sf9 insect cells in presence of 0.001 mM of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human JAK2 expressed in Sf9 insect cells in presence of 0.001 mM ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK1/JAK2 in human HEKa cells assessed as reduction in IL-31-induced STAT3 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK1/TYK2 in human HEKa cells assessed as reduction in IL-13-induced STAT6 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human JAK2 expressed in Sf9 insect cells by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK1/JAK3 in human T cell assessed as reduction in IL-2-induced STAT5 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK1 in human TF-1 cells assessed as reduction in IL-6-induced STAT3 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 14nMAssay Description:Inhibition of JAK1 in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 19nMAssay Description:Inhibition of JAK1/JAK2 in human CD14-positive cell assessed as reduction in IFNgamma-induced STAT1 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 22nMAssay Description:Inhibition of JAK1/JAK3 in human T cell assessed as reduction in IL-15-induced STAT5 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human JAK1 (845 to 1142 residues) expressed in Sf9 insect cells in presence of 0.1 mM of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human JAK1 (845 to 1142 residues) expressed in Sf9 insect cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human JAK3 (811 to 1103 residues) expressed in Sf9 insect cells in presence of 0.001 mM ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 55nMAssay Description:Inhibition of N-terminal/C-terminal his-tagged recombinant human TYK2 (880 to 1185 residues) expressed in Sf9 insect cells in presence of 0.1 mM by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human JAK3 (811 to 1103 residues) expressed in Sf9 insect cells by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 78nMAssay Description:Inhibition of JAK1 in human CD14-positive cell assessed as reduction in IL-6-induced STAT3 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human JAK2 expressed in Sf9 insect cells in presence of 0.1 mM ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human JAK2 expressed in Sf9 insect cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 207nMAssay Description:Inhibition of JAK1 in human CD3-positive T cell assessed as reduction in IL-6-induced STAT3 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 420nMAssay Description:Inhibition of Rock2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 593nMAssay Description:Inhibition of JAK2 in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 649nMAssay Description:Inhibition of JAK1 in human UT7 cells assessed as reduction in Epo-induced STAT5 phosphorylation by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 920nMAssay Description:Inhibition of Rock1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of KDR (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of JAK3 in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human JAK3 (811 to 1103 residues) expressed in Sf9 insect cells in presence of 0.1 mM ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CAMK1D (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human JAK3 (811 to 1103 residues) expressed in Sf9 insect cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of RET (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of LTK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2 [5-1181](Mouse)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of TYK2 in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Aurora 2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of N-terminal/C-terminal his-tagged recombinant human TYK2 (880 to 1185 residues) expressed in Sf9 insect cells in presence of 0.001 mM by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 4.96E+3nMAssay Description:Inhibition of N-terminal/C-terminal his-tagged recombinant human TYK2 (880 to 1185 residues) expressed in Sf9 insect cells by Cheng-Prusoff equation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of TNK2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Aurora 1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of ALK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG protein-coupled receptor kinase 5(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of GRK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of Rsk2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 16(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of STK16 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-dependent protein kinase 1(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKG1A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein kinase C zeta type(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKA (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38 alpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase D3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRKCN (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
AbbVie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50503287(ABT-494 | Rinvoq | Upadacitinib | US10961228, Exam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
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