Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50008704
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521402(CHEMBL4471834)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM67506(4-(4,5-diphenyl-1,3-dihydroimidazol-2-ylidene)-2,6...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521405(CHEMBL4551018)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521420(CHEMBL4467223)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521404(CHEMBL4449307)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521425(CHEMBL4449305)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521419(CHEMBL1342201)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521406(CHEMBL4458407)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521413(CHEMBL4565746)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521408(CHEMBL4468906)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521407(CHEMBL4577390)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521399(CHEMBL4588691)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521428(CHEMBL4471548)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521427(CHEMBL4533205)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521421(CHEMBL4514045)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521430(CHEMBL4573101)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521412(CHEMBL4540577)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521429(CHEMBL4436316)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521410(CHEMBL4441694)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521423(CHEMBL4556374)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521422(CHEMBL4476341)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521409(CHEMBL4585573)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521400(CHEMBL4554915)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521426(CHEMBL4438348)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521415(CHEMBL4440577)
Affinity DataIC50: 560nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521433(CHEMBL4452820)
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Rat)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521403(CHEMBL4454046)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat brain neutral sphingomyelinase pre-incubated for 30 mins before p-nitrophenyl/phosphorylcholine substrate addition by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521432(CHEMBL4550884)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM29040(cambinol)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521431(CHEMBL4575266)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521418(CHEMBL1440191)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521401(CHEMBL4559885)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521416(CHEMBL4472289)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521417(CHEMBL4454235)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521414(CHEMBL4449851)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521411(CHEMBL4452837)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 3(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50521424(CHEMBL4463647)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nSMase expressed in HEK293 cells using sphingomyelin as substrate by alkaline phosphatase, choline oxidase and horser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed