Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010121
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  20nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535381(CHEMBL4591419)
Affinity DataEC50:  300nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535382(CHEMBL4588863)
Affinity DataEC50:  460nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  500nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535385(CHEMBL4455475)
Affinity DataEC50:  670nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535371(CHEMBL4455911)
Affinity DataEC50:  730nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535377(CHEMBL4553281)
Affinity DataEC50:  740nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535370(CHEMBL4448603)
Affinity DataEC50:  810nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535387(CHEMBL4585144)
Affinity DataEC50:  830nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535369(CHEMBL4461163)
Affinity DataEC50:  940nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535367(CHEMBL4456883)
Affinity DataEC50:  1.09E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535372(CHEMBL4532035)
Affinity DataEC50:  1.15E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535379(CHEMBL4445722)
Affinity DataEC50:  1.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535376(CHEMBL4451432)
Affinity DataEC50:  1.59E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535374(CHEMBL4591348)
Affinity DataEC50:  2.06E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535378(CHEMBL4562865)
Affinity DataEC50:  2.80E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535383(CHEMBL4436469)
Affinity DataEC50:  2.93E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535386(CHEMBL4535914)
Affinity DataEC50:  3.59E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535368(CHEMBL4450943)
Affinity DataEC50:  4.37E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535380(CHEMBL4578551)
Affinity DataEC50:  5.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535375(CHEMBL4592387)
Affinity DataEC50:  6.67E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535373(CHEMBL4471591)
Affinity DataEC50:  1.02E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535384(CHEMBL4465344)
Affinity DataEC50:  1.97E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  2.00E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)