Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50010128
TargetCytochrome P450 2D6(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50535429(CHEMBL4450031)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human microsomal CYP2D6 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50535429(CHEMBL4450031)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50535429(CHEMBL4450031)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human microsomal CYP2C19 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50535429(CHEMBL4450031)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human microsomal CYP2C9 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50535429(CHEMBL4450031)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human microsomal CYP3A4 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50535429(CHEMBL4450031)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed