Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50008804
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM441913(US10647694, Example 45 | US10647694, Example 43 | ...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM441926(US10647694, Example 14)
Affinity DataIC50: 37nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM441913(US10647694, Example 45 | US10647694, Example 43 | ...)
Affinity DataIC50: 37nMAssay Description:Inhibition of ALK F1174L mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 48nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM441926(US10647694, Example 14)
Affinity DataIC50: 52nMAssay Description:Inhibition of ALK F1174L mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 63nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM441913(US10647694, Example 45 | US10647694, Example 43 | ...)
Affinity DataIC50: 71nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM441926(US10647694, Example 14)
Affinity DataIC50: 106nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 109nMAssay Description:Inhibition of ALK F1174L mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 114nMAssay Description:Inhibition of ALK F1174L mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 170nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 198nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)