Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50010141
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 10nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 13nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 13nMAssay Description:Inhibition of human full length MINK1(1-1332)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 13nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 16nMAssay Description:Inhibition of human full length MINK1(1-1332)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 32nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 32nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 40nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 40nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 40nMAssay Description:Inhibition of human full length MINK1(1-1332)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 50nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 79nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535494(CHEMBL4527085)
Affinity DataIC50: 126nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 126nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535494(CHEMBL4527085)
Affinity DataIC50: 158nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 199nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535494(CHEMBL4527085)
Affinity DataIC50: 200nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 470nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 501nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535492(CHEMBL4558988)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535492(CHEMBL4558988)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human full length MINK1(1-1332)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535492(CHEMBL4558988)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human full length MINK1(1-1332)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535492(CHEMBL4558988)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535492(CHEMBL4558988)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandPNGBDBM50535493(CHEMBL4465524)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535492(CHEMBL4558988)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535493(CHEMBL4465524)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535493(CHEMBL4465524)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535493(CHEMBL4465524)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human full length TNIK(1-1360)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535493(CHEMBL4465524)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human full length TNIK in HEK293 cells co-transfected with full length SMAD1 incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
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