Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50008030
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514996(CHEMBL4587332)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514994(CHEMBL4444154)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514993(CHEMBL4435374)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514995(CHEMBL4552684)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514997(CHEMBL4531384)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514992(CHEMBL4522253)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed