Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50010149
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535645(CHEMBL4553532)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535648(CHEMBL4450014)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535646(CHEMBL4559776)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535644(CHEMBL4562534 | US11174248, Example 24)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535643(CHEMBL4579292)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535647(CHEMBL4442821 | US11174248, Example 48)
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed