Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50007006
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human TASK1 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human TASK1 expressed in CHO cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50: 35nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 36nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human TASK3 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50054472(Methanandamide | (R)-Methanandamide | (5Z,8Z,11Z,1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human TASK1 expressed in African green monkey COS cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123508([2'-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylm...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505292(CHEMBL4592278)
Affinity DataIC50: 220nMAssay Description:Inhibition of human TASK1 by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505292(CHEMBL4592278)
Affinity DataIC50: 222nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50: 243nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50: 300nMAssay Description:Inhibition of human TASK1 expressed in HEK293 cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 318nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505295(CHEMBL4468526)
Affinity DataIC50: 350nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505297(CHEBI:681848 | Doxapram)
Affinity DataIC50: 410nMAssay Description:Inhibition of rat TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505299(CHEMBL1557966)
Affinity DataIC50: 413nMAssay Description:Inhibition of human TASK3 expressed in HEK293 by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50417943(CHEMBL1671897)
Affinity DataIC50: 600nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505292(CHEMBL4592278)
Affinity DataIC50: 950nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50: 990nMAssay Description:Inhibition of human TASK3 expressed in CHO cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505294(CHEMBL4441986)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22988(Arachidonoyl ethanolamide | Arachidonoylethanolami...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human TASK1 expressed in African green monkey COS7 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505299(CHEMBL1557966)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human TASK1 by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 17(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human TASK4 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 5(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human TASK2 expressed in CHO cells by Inside-out macro-patches based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505297(CHEBI:681848 | Doxapram)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM78934(MLS001056800 | Mibefradil dihydrochloride hydrate ...)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505297(CHEBI:681848 | Doxapram)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of rat TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50225497(CHEBI:4904 | Duranest [as hydrochloride] | Etidoca...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50350790(Bupivacaine | BUPIVACAINE HYDROCHLORIDE | SAMPL3, ...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50350790(Bupivacaine | BUPIVACAINE HYDROCHLORIDE | SAMPL3, ...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of rat TASK1 expressed in African green monkey COS7 cells by outside-out patches based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM79212((2R,3R)-2-(diphenylmethyl)-N-[(2-iodophenyl)methyl...)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50442906(Oligomycin)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50099963(N*4*-(1-Benzyl-1H-indazol-5-yl)-N*6*,N*6*-dimethyl...)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505291(CHEMBL4564685)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50239375(CHEBI:8890 | Ropivacaine)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22876(Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...)
Affinity DataIC50: 6.34E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505300(CHEMBL4458347)
Affinity DataIC50: 7.38E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22872(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
Affinity DataIC50: 7.38E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM22872(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
Affinity DataIC50: 7.38E+4nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505298(CHEMBL4461580)
Affinity DataIC50: 8.35E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505293(CHEMBL4439787)
Affinity DataIC50: 9.67E+4nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Rat)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50350790(Bupivacaine | BUPIVACAINE HYDROCHLORIDE | SAMPL3, ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat TASK3 expressed in African green monkey COS7 cells by outside-out patches based electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50011036(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 1.59E+5nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Ti+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505296(CHEMBL4521731)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50017662(CHEMBL79 | N-(2,6-dimethylphenyl)-N(2),N(2)-diethy...)
Affinity DataIC50: 2.22E+5nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 9(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50505301(CHEMBL4466298)
Affinity DataIC50: 2.68E+5nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50017659(Diaethylaminoaethanol ester der p-butylaminobenzoe...)
Affinity DataIC50: 6.68E+5nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPotassium channel subfamily K member 3(Human)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50417964(Carbocaine | MEPIVACAINE)
Affinity DataIC50: 7.09E+5nMAssay Description:Inhibition of human TASK1 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed